Nephroprotective Effect Of Camellia sinensis L. On Lead Acetate Induced Male Albino Rats

Protective effect of Camellia Sinensis L. leaf extract on lead acetate Induced nephrotoxicity in albino wistar rats were investigated by analyzing various biochemical parameters. Lead acetate induced kidney damage was well manifested by significant increase in renal parameters like urea, uric acid creatinine and serum electrolytes sodium, potassium,chloride, calcium, phosphorous and TBARS and decrease the levels of haemoglobin and protein. The oral administration of aqueous extract of camellia sinensis along with lead acetate reversed these altered parameters to normal level which indicating the nephroprotective efficacy of camellia sinensis against lead acetate induced kidney injury. From this , we concluded the phytochemical constituents such as flavonoids are responsible for the nephroprotective activity of camellia sinensis. Further extensive studies are required for its potential uses in clinical practice.